A Novel Translocation , t ( 2 ; 5 ) ( p 23 ; q 35 ) , in Childhood Phagocytic Large T - Cell Lymphoma Mimicking Malignant
نویسندگان
چکیده
We report a novel chromosome translocationt(2;5)(p23;q35) or its variant. t(2;5;13)(p23;q35;q12)-in 3 patients with peripheral T-celI lymphoma. All 3 were female children who had peripheral lymphadenopathy without organomegaly and underwent complete remission with or without chemotherapy. Their tumors were characterized histologically by predominant large cells, at times showing phagocytosis, and immunologically by peripheral T-ceIl phenotype and expression of Ki-1 antigen and epi-
منابع مشابه
A novel translocation, t(2;5)(p23;q35), in childhood phagocytic large T-cell lymphoma mimicking malignant histiocytosis.
We report a novel chromosome translocation--t(2;5)(p23;q35) or its variant, t(2;5;13)(p23;q35;q12)--in 3 patients with peripheral T-cell lymphoma. All 3 were female children who had peripheral lymphadenopathy without organomegaly and underwent complete remission with or without chemotherapy. Their tumors were characterized histologically by predominant large cells, at times showing phagocytosis...
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